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Footnotes
Contributors JD wrote the first draft. All authors contributed to editing the manuscript and approved the final version.
Funding This study was funded by the National Institute on Drug Abuse (grant number: 1R01DA046226; PI: Katherine E Watkins) and the National Institute on Aging (grant number: 5P30AG024968; MPI: Jason N Doctor and Dana Goldman). The funder did not have a role in the design and conduct of the study; the collection, management, analysis and interpretation of the data; preparation, review or approval of the manuscript; or decision to submit the manuscript for publication.
Competing interests JD receives funding from the National Institutes of Health and Edwards Lifesciences.
Provenance and peer review Not commissioned; externally peer reviewed.