Example of a combined study characteristics and key outcome evidence table
Author, year Risk of bias | Total N Follow-up | Inclusion criteria | Exclusion criteria | Intervention and control | Weight change, BMI |
Cohen, 2020 Moderate | N=100 2 years | Age: 18–65 years; BMI: 30–34.9 kg/m2; >15 years history of T2DM; early stage chronic kidney disease | Autoimmune or T1DM; prior abdominal surgery; alcoholism or severe hepatic disease | Intervention: RYGB Control: MT Best medical treatment consistent with updated 2019 ADA and EASD guidelines | Baseline: RYGB: 32.5 kg/m2 MT: 32.6 kg/m2 2 years: RYGB: 24.5 kg/m2 MT: 31.2 kg/m2 Mean difference: −6.9 kg/m2 (range −8.0 to −5.8 kg/m2), p<0.001 |
Adapted from Durbin et al. 8
ADA, American Diabetes Association; BMI, body mass index; EASD, European Association for Study of Diabetes; MT, medical therapy; RYGB, Roux-en-Y gastric bypass; T1DM, type 1 diabetes; T2DM, type 2 diabetes.